Nuclear and Chromatin Dynamics

3 - 4 Jul 2022, 9.00 AM - 5.00 PM

SUMO modification in cell signalling

Montpellier, France

Post-translational Modifications (PTMs) act at the core of every biological system. PTM events generate proteoforms that orchestrate cell signalling in almost every biological process.

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Katja Graumann

Biography

Katja is a senior lecturer in cell biology at Oxford Brookes University, department of biological and medical sciences, and had previously held a Leverhulme Trust early career fellowship there. Her research interest in the plant nuclear envelope started during her PhD, when she thought to identify novel, plant nuclear envelope components.

Since then, she has focused on elucidating the structural and functional significance of the nuclear envelope in higher plants, particularly looking at protein bridges that cross the membrane system to connect cellular and nuclear components.

Christophe Tatout

Biography

Christophe is professor in genetics and epigenetics at Université Clermont Auvergne (UCA), Department of Biology and leads a research team at the Institute of Genetics, Reproduction and Development (iGReD).

In the early part of his scientific career (1990-1999), he contributed to Drosophila genetics working on transposable elements and Polycomb regulation, then moved to industry to lead maize and wheat genomic projects before joining UCA as a Professor in 2009. From 2017-2021 Christophe chaired the COST-Action INDEPTH (CA16212, Impact of Nuclear Domains On Gene Expression and Plant Traits; https://www.brookes.ac.uk/indepth/) bringing together researchers working towards a better understanding of how epigenetics and nuclear structure modulate gene expression to regulate complex plant traits.

He is heading the Master of bioinformatics at UCA and applies 3D imaging methods to study nuclear dynamics. His current research focuses on how chromatin domains are formed, maintained and positioned in nuclear space in particular through interaction with protein components of the nuclear envelope. To investigate this question, he developed specific image analysis methods for 3D nuclei.

Christophe Tatout
University Clermont Auvergne
Institute of Genetics, Reproduction & Développement (iGReD) - France.